Superantigens: Gazing into the crystal ball

Superantigens: Gazing into the crystal ball

The recently determined crystal structures of complexes between bacterial toxin 'superantigens' and MHC class II molecules shed light on the nature of the interactions between these two molecules.

Gazing into a crystal ball to predict kidney transplant outcome.

Kidney transplantation is the optimal therapy for end-stage kidney disease but requires lifelong immunosuppression. Despite improvements in immunosuppression regimens that have reduced rates of acute transplant rejection, long-term allograft survival remains suboptimal. More than 50% of transplanted kidneys from deceased donors fail within 10 years. In order to improve long-term outcomes, physi...

Crystal ball gazing and the effects of fate.

[gazing into a Crystal Ball and Detecting Subjects at Risk for Developing Cutaneous Melanoma].

Cutaneous melanoma is the deadliest skin cancer showing an increasingly growing incidence in white populations of Europe and United States. Intensive research in recent years has begun to unlock its molecular pathogenesis. Screening the neoplasm at an early stage remains primordial. Hence, targeting populations at risk is likely efficient. In such an attempt, the regular clinical examination be...

Looking into the crystal ball